[Answer] Which molecules do not normally cross the nuclear membrane?

Answer: DNA

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Which molecules do not normally cross the nuclear membrane? The cytoplasmic protein contains a nuclear localization signal. Nucleoplasmin does not have a nuclear localization signal. One of the fusion proteins entered the nucleus by passive transport. Only one of the two fusion proteins possesses a nuclear localization signal. Large proteins containing a nuclear localization signal (NLS) bind to the nuclear pore and enter the nucleus without any expenditure of energy. False A small protein is injected into a cell and observed in the nucleus a short time later. Large molecules such as glucose can not cross the lipid bi layer can still move across the membrane with a concentration gradient by water. Carbon dioxide and oxygen will move large molecules ... Hence DNA would be the molecule that will most likely never cross the nuclear membrane. Rest all molecules like the gene regulatory proteins mRNA RNA processing proteins etc are selectively monitored and they pass in and out of the nuclear membrane. The nuclear membrane can be described as a lipid bi-layer membrane which surrounds the nucleus and is only present in the eukaryotic cells. Wed Sep 14 2011 · Best Answer: D DNA A mRNA It exits the nucleus to be translated by ribosomes in the c...

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