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1/10/21

[Answer] What is synteny?

Answer: -The condition of two or more genes being located on the same chromosome whether or not there is demonstrable linkage between them (i.e. region 2 in mouse chromosome 1 vs. human chromosome 2).




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What is synteny? Synteny | definition of synteny by Medical dictionary Synteny - Wikipedia Synteny - CoGepedia Synteny - CoGepedia In classical genetics synteny describes the physical co-localization of genetic loci on the same chromosome within an individual or species. Today however biologists usually refer to synteny as the conservation of blocks of order within two sets of chromosomes that are being compared with each other. This concept can also be referred to as shared synteny. The classical concept is related to genetic linkage : Linkage between two loci is established by the observation of lower-than-expected recombination frequencies between them. In contrast any loci on the same chromosome are by definition syntenic even if their recombination frequency cannot be … This concept can also be referred to as shared synteny. The classical concept is related to genetic linkage : Linkage between two loci is established by the observation of lower-than-expected recombination frequencies between them. In contrast any loci on the same chromosome are by definition syntenic even if their recombination frequency cannot be distinguished from unlinked loci by practical experiments. Thus in theory all linked loci are syntenic but not all syntenic loci are necessarily linked. Similarly in genomics the genetic loci on a chromosome are syntenic regardless of whether this relationship can be established by experimental methods such as DNA sequencing /assembly genome walking physical localization or hap-mapping . Students of genetics employ the term synteny to describe the situation in which two genetic loci have been assigned to the same chromosome but still may be separated by a large enough distance in map units that genetic linkage has not been demonstrated. The Encyclopædia Britannica gives the following description of synteny: Genomic sequencing and mapping have enabled compariso...


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