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3/7/21

[Answer] What is the role of tRNA?

Answer: -carries amino acids to the ribosome and matches them to the coded mRNA message




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What is the role of tRNA? While the specific nucleotide sequence of an mRNA specifies which amino acids are incorporated into the protein product of the gene from which the mRNA is transcribed the role of tRNA is to specify which sequence from the genetic code corresponds to which amino acid. The mRNA encodes a protein as a series of contiguous codons each of which is recognized by a particular tRNA. One end of the tRNA matches the genetic code in a three-nucleotide sequence called the anticodon. The anticodon forms three Aminoacyl-tRNA (also aa-tRNA or charged tRNA) is tRNA to which its cognate amino acid is chemically bonded (charged). The aa-tRNA along with particular elongation factors deliver the amino acid to the ribosome for incorporation into the polypeptide chain that is being produced during translation. Alone an amino acid is not the substrate necessary to allow for the formation of peptide bonds within a growing polypeptide chain. Instead amino acids must be "charged" or aminoacylated with a tRNA to for… From Wikipedia the free encyclopedia Amino acid activation (also known as aminoacylation or tRNA charging) refers to the attachment of an amino acid to its Transfer RNA (tRNA). Aminoacyl transferase binds Adenosine triphosphate (ATP) to amino acid PP is released. Aminoacyl TRNA synthetase binds AMP-amino acid to tRNA. Aminoacyl tRNA synthetase - Wikipedia Aminoacyl-tRNA - Wikipedia The first non-coding RNA to be characterised was an alanine tRNA found in baker's yeast its structure was published in 1965. To produce a purified alanine tRNA sample Robert W. Holley et al. used 140kg of commercial baker's yeast to give just 1g of purified tRNA Ala for analysis. ...

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