Answer: Because the higher the pH the higher activity.
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How does pH affect the lipase activity?
Henry Louis Le Chatelier was a French chemist of the late 19th and early 20th centuries. He devised Le Chatelier's principle used by chemists and chemical engineers to predict the effect a changing condition has on a system in chemical equilibrium.
Effects of pH on Amylase Activity Essay Example for Free
Effects of pH (Introduction to Enzymes)
How Does pH Level Affect Enzyme Activity? | Sciencing
How Does pH Level Affect Enzyme Activity? | Sciencing
Mon Apr 24 2017 · A pH environment has a significant effect on an enzymes. It can affect the intramolecular forces and change the enzyme's shape -- potentially to the point where it is rendered ineffective. With these effects in mind typical enzymes have a pH range in which they perform optimally. For example alpha amylase which found in the mouth operates most effectively near a neutral pH .
When the pH drops below pH 8.3 phenolphthalein goes colourless. Here an alkaline solution of milk lipase and phenolphthalein will change from pink to colourless as the fat in milk is broken down to form fatty acids (and glycerol) thus reducing the pH to below 8.3.
Enzyme activity is at its maximum value at the optimum pH . As the pH value is increased above or decreased below the optimum. pH the enzyme activity decreases .
Let us first clear out some basic concepts regarding lipase colipase and bile salts. The pancreatic lipase has an optimum pH range of about pH 8.0 (Worthington). This can be understood easily by Le Chatelier's principle: as the reaction moves forward there is reduction of pH (due to formation of fatty acids). So a basic pH would help the reaction in moving forward.
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